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KMID : 0616119820130010033
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Korean Journal of Pharmacognosy
1982 Volume.13 No. 1 p.33 ~ p.38
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Studies on the Efficacy of the Combined Preparation of Crude Drugs ( Ⅵ ) Effect of “Saengkankunbi - Tang ”on activities of the Liver Enzyme , Protein contents and the Excretory Action of Bile Juice in the Serum of CCl4 intoxicated Rabbits
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홍남두/Hong ND
김종우/김병훈/손정곤/Kim JW/Kim BW/Shon JG
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Abstract
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In order to investigate the pharmacological action of the combined preparation of crude drugs, "Saengkankunbi-Tang" were studied. These studies were conducted in an attempt to investigate the effect of "Saengkankunbi-Tang" on activities of the liver enzyme, protein contents and the excretory action of bile juice in the serum of CCl₄-intoxicated rabbits. The results of this investigate were summerized as follows; GOT, GPT activities and total cholesterol contents in the serum of rabbits induced by CCl₄ were shown to the remarkable decrease with the passage of the time in the oral administration of the sample. Albumin contents in the serum of rabbits induce by CCl₄ were noted to the significant increase with the passage of the time. Serum total protein contents were noted to the significant increase only the 4th and 6th day. BSP accumulation contents in the serum of rabbits induced by CCl₄ showed the remarkable decrease with the passage of the time.
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KEYWORD
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